This topic has only recently been consistently addressed as an issue on its own apart from the rest of the lymphomas and this text is the first to apply modern systems of classification diagnosis and management. Lymphomas classically manifest themselves in the lymph nodes but can also present in other bodily tissues or systems the organ where exactly they present may. Primary extranodal b cell lymphoma current concepts and treatment strategies barbara vannata emanuele zucca oncology institute of southern switzerland ospedale san giovanni bellinzona switzerland. Proposed definitions of extranodal lymphoma vary according to purpose from lymphomas restricted to a single extranodal site and its regional lymph nodes to lymphomas which may be more widespread but in which an extranodal organ is the presenting and predominant site of disease to which therapy may be primarily aimed. Introduction extranodal nk t cell lymphoma nasal type is a distinct clinicopathologic entity the most common initial site of presentation is the nasopharyngeal area but non nasals sites including the skin and the gastrointestinal tract may be affected areas covered the diagnosis and management
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